Influence of Group on Individual Subject Maps in SPM Voxel Based Morphometry
نویسندگان
چکیده
منابع مشابه
Influence of Group on Individual Subject Maps in SPM Voxel Based Morphometry
Voxel based morphometry (VBM) is a widely utilized neuroimaging technique for spatially normalizing brain structural MRI (sMRI) onto a common template. The DARTEL technique of VBM takes into account the spatial intensity distribution of sMRIs to construct a study specific group template. The group template is then used to create final individual normalized tissue maps (FINTM) for each subject i...
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Within-group nonlinear registration improves between-group Voxel-Based Morphometry
Accurate registration is imperative for VBM methodologies. Typically, linear and/or nonlinear registration is used to conform all brains to the same shape, orientation and size. We suggest disease-specific reference targets to reduce normal inter-subject anatomical variability while at the same time enhance pathologically-induced differences between groups. These targets can be created by avera...
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Gray matter volumetry (i.e., atlas-based volumetry [1, 2]) and morphometry (i.e., voxel-based morphometry (VBM) [3]) using three-dimensional T1-weighted magnetic resonance images (3D-T1WIs) with spatial normalization have been used to estimate local brain volume in normal subjects [4 –7] and in patients (e.g., in Alzheimer’s disease (AD) [8], epilepsy[9], diabetes [10], and panic disorder [11])...
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The human brain is in a state of constant change and adaptation. This may be driven either by normal developmental or aging processes or by the effects of learning, training, and new occurrences in daily life. In addition to these aforementioned changes, more systematic influences such as gender, disease, and genes affect the brain’s structure. Using magnetic resonance imaging, brain changes an...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2016
ISSN: 1662-453X
DOI: 10.3389/fnins.2016.00522